In addition to singing, Luster also played guitar. He and his bass-playing brother Richard (“Ricky”) learned to play the hits of their favorite quartets so whenever those groups performed in Durham, the brothers would be ready to fill in as musicians if needed. The strategy worked; in 1981, both brothers not only played for, but also began touring with, the Highway QCs. They can be heard accompanying the QCs on the group’s 1983 Savoy Records release, Something’s on My Mind (That’s Worrying Me).

Darrell got the chance to work with the Sensational Nightingales in 1982 when he filled in for longtime members Jo Jo Wallace and Bill Woodruff, who were ill. When the ’Gales lead singer Charles Johnson left to form the Revivers, he invited the two Luster brothers to join him. Darrell and Ricky joined the Revivers in 1984 and sang on all of the Revivers’ albums, including that year’s Malaco release, No Man Can Stand Alone, until they parted ways with the group in 1993.

At that point, Darrell tried his hand at being a solo artist. His first album, Peace Be Still, came out on Morning Star Records and included the single I Believe He Died for Me. In 1997, he released Members Only and It Doesn’t All End at the Grave on his own label, Beacon Records.

Luster reunited with the Sensational Nightingales in October 1999 when Malaco Records hired him to produce an album by the veteran quartet. Two albums later, Luster was a bona fide singing member of the group. A Luster-produced album for Malaco, Songs to Edify, earned the ’Gales a Grammy nomination for Best Traditional Soul Gospel Album.

Luster became Malaco’s in-house producer in 2006. He collaborated on the Yes! Quartet campaign, which produced a Stellar Award–nominated compilation featuring the Pilgrim Jubilees, Slim and the Supreme Angels, the Sensational Nightingales and Spencer Taylor and the Highway QCs.

Luster also produced Malaco’s A Soul Stirring Reunion in 2009. This album, also nominated for a Stellar Award, reunited past and present members of the Soul Stirrers, including Leroy and Arthur Crume, Willie Rogers, Eddie Huffman and the Reverend Luther Gamble. In addition to the Nightingales and Soul Stirrers, Luster has produced, written for and sung on Malaco albums by the Brooklyn All Stars and Margaret “Babe” Allison and the Angelic Gospel Singers. His duet with the Reverend F.C. Barnes on the traditional-sounding God Is God (He Won’t Change) became a radio hit for Atlanta International Records in 2010.

Today, Darrell Luster is head of A&R and promotions for the gospel division of Malaco, which includes the gospel catalog of Savoy Records, and is director of Malaco’s 4 Winds label. He also hosts his own radio show. In 2017, Luster was honored by the Charlotte, North Carolina–based Gospel Image Awards with a Lifetime Achievement Award.